Ivermectin
Ividiyo
Ivermectin
Ivermectinngumgubo omhlophe oyikristale, ongenavumba.Inyibilika ngokukhululekileyo kwi-methanol, i-ethanol, i-acetone, i-ethyl acetate, ayinyibiliki ngokuthe ngqo emanzini, kunye ne-hygroscopic kancinane.Ivermectin i semisynthetic macrolide multi-component antibiotic, equlathe ikakhulu ivermectin B1 (Bla + B1b) umxholo ongekho ngaphantsi kwama-95%, apho umxholo Bla ongekho ngaphantsi kwama-85%.
Umgaqo Wezonyango
Ivermectin inempembelelo ekhethiweyo yokuthintela, ngokuzibophelela kubudlelwane obuphezulu bemijelo ye-chloride kunye ne-glutamate njengevalve kwiiseli zemithambo-luvo kunye neeseli zezihlunu zezilwanyana ezingenaspinless, ezikhokelela ekwandeni kokungena kweembrane zeseli kwi-ion ye-chloride, kubangela i-hyperpolarization yeeseli ze-nerve. okanye iiseli zezihlunu, kwaye ibangela ukukhubazeka okanye ukufa kwee-parasites.Ikwasebenzisana ne-chloride channels zezinye iivalve ze-ligand, ezifana ne-neurotransmitter g-aminobutyric acid (GABA).Ukukhethwa kwale mveliso kungenxa yokuba ezinye izilwanyana ezincelisayo azinayo i-glutamate-chloride channels kwi-vivo, kwaye i-avermectin inobudlelwane obuphantsi kuphela kwiitshaneli ze-mammalian ligand-chloride.Le mveliso ayikwazi ukungena kumqobo wegazi-ingqondo yomntu.I-Onchocerciasis kunye ne-strongyloidiasis kunye ne-hookworm, i-ascaris, i-Trichuris trichiura, kunye nosulelo lwe-Enterobius vermicularis.
Ukusebenzisa
Ivermectin liyeza elisetyenziselwa ukunyanga iintlobo ezininzi ze-parasite infestations.Ivermectin isetyenziselwa ukunyanga izilwanyana izifo ezibangelwa yi roundworms kunye ectoparasites.
Ivermectin isetyenziswa rhoqo ukulawula iintshulube parasitic kwi phecana emathunjini izilwanyana ruminant.Ezi zifunxi-gazi zidla ngokungena esilwanyaneni xa sisatya, zidlule emathunjini, zize zihlale kwaye zivuthwe emathunjini, emva koko zivelise amaqanda ashiya isilwanyana ngendle yaso kwaye anokuhlasela amadlelo amatsha.I-Ivermectin iyasebenza ekubulaleni ezinye, kodwa hayi zonke, kwezi zifunxi-gazi.Kwizinja isetyenziswa rhoqo njengeprophylaxis ngokuchasene neheartworm.
Kwiyeza lezilwanyana, isetyenziselwa ukuthintela kunye nokunyanga i-heartworm kunye ne-acariasis, phakathi kwezinye izibonakaliso.Inokuthi ithathwe ngomlomo okanye isetyenziswe esikhumbeni ngenxa yokuhlaselwa kwangaphandle.Ivermectin isetyenziswa ngokubanzi nematodes emathunjini, lungworms, kunye parasitic arthropods ezinkomeni, iigusha, amahashe, neehagu, nematodes intestinal ezinjeni, imites indlebe, Sarcoptes scabiei, intliziyo filariae, kunye microfilariae, kunye nematodes emathunjini kunye nematodes emathunjini.
Amalungiselelo
Ivermectin bolus;
Ivermectin yokugalela isisombululo 0.5%,1% ;
Ivermectin gel 0.4%
I-Hebei Veyong Pharmaceutical Co., Ltd, yasekwa kwi-2002, ehlala kwisiXeko saseShijiazhuang, kwiPhondo laseHebei, eChina, ecaleni kwe-Capital Beijing.Ulishishini elikhulu leyeza lezilwanyana eliqinisekisiweyo le-GMP, eline-R&D, imveliso kunye nokuthengiswa kwee-APIs zonyango lwezilwanyana, amalungiselelo, ukutya okuxutywe kwangaphambili kunye nezongezo zokutya.NjengeZiko lobuGcisa lePhondo, iVeyong iye yaseka inkqubo yeR&D ehlaziyiweyo yeyeza elitsha lezilwanyana, kwaye lishishini elaziwa kuzwelonke leteknoloji esekelwe kunyango lwezilwanyana, kukho iingcali zobugcisa ezingama-65.I-Veyong ineziseko ezimbini zokuvelisa: i-Shijiazhuang kunye ne-Ordos, apho isiseko se-Shijiazhuang sihlanganisa indawo ye-78,706 m2, kunye neemveliso ze-API ze-13 ezibandakanya i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kunye ne-11, i-injection oral solutions, i-injection oral solutions. , i-premix, i-bolus, i-pesticides kunye ne-disinfectant, njl.IVeyong ibonelela ngee-APIs, ngaphezulu kwe-100 yamalungiselelo eleyibhile, kunye nenkonzo ye-OEM & ODM.
I-Veyong ibona ukubaluleka okukhulu kulawulo lwenkqubo ye-EHS(Environment, Health & Safety), kwaye ifumene i-ISO14001 kunye nezatifikethi ze-OHSAS18001.I-Veyong idweliswe kumashishini amashishini asakhasayo anobuchule kwiPhondo laseHebei kwaye inokuqinisekisa ukubonelela ngokuqhubekayo kweemveliso.
I-Veyong yaseka inkqubo epheleleyo yolawulo lomgangatho, yafumana isatifikethi se-ISO9001, isatifikethi se-GMP sase-China, isiqinisekiso se-APVMA se-GMP sase-Australia, isatifikethi se-GMP sase-Ethiopia, isatifikethi se-Ivermectin CEP, kwaye siphumelele ukuhlolwa kwe-US FDA.I-Veyong ineqela lobuchwephesha lobhaliso, intengiso kunye nenkonzo yobugcisa, inkampani yethu ifumene ukuthembela kunye nenkxaso kubathengi abaninzi ngomgangatho wemveliso ogqwesileyo, umgangatho ophezulu wokuthengisa kwangaphambili kunye nenkonzo yasemva kokuthengisa, ulawulo olunzulu kunye nolwenzululwazi.I-Veyong yenze intsebenziswano yexesha elide kunye namashishini amaninzi amachiza ezilwanyana awaziwayo ngamazwe ngamazwe kunye neemveliso ezithunyelwa eYurophu, eMzantsi Melika, kuMbindi Mpuma, e-Afrika, e-Asia, njl. ngaphezu kwamazwe angama-60 kunye nemimandla.