Closantel Sodium
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Closantel Sodium
I-sodium ye-Closantel yi-anthelmintic ebanzi, enefuthe elihle kwiintlobo ezahlukeneyo ze-trematodes, i-nematodes kunye ne-arthropod larvae;umsebenzi wayo wokugxotha umkhuhlane ikakhulu ngokuchasene neFasciola hepatica, anti-nematodes kunye Umsebenzi wokugxotha imibungu ngokuchasene nearthropods ijolise ikakhulu kuzo zonke iintlobo zeentshulube ezifunxa igazi okanye iplasma.
Le mveliso isetyenziswa kakhulu kwizifo ezahlukeneyo ezichazwe ngasentla kwizilwanyana kunye neegusha.Inokulawulwa ngomlomo okanye ngomzali (i-subcutaneously kunye ne-intramuscularly), kwaye ineempembelelo zonyango kunye nokukhusela.Kukho iinaliti, iipilisi kunye nee-agent zokumanzisa kwimarike.Ngokubanzi, iyahambelana ne-mebendazole kunye nezinye iimveliso ze-benzimidazole ukwenza into edibeneyo yokufunxa iigusha;iyahambelana nelevamisole ukwenza ipilisi edibeneyo yenkomo.
Indlela yokwenza kunye neempawu
I-Closalamide sodium ikwabizwa ngokuba yi-chlorsalamide sodium ityuwa kunye ne-chlorsalamide sodium ityuwa.Ikwikhompawundi efanayo yesalicylanilide njenge-iodosalamide kwaye luhlobo olutsha lwe-anti-parasitic ebanzi esetyenziswa ngoku kushishino lokufuya.Iyeza lezinambuzane, imbonakalo ingumgubo otyheli kancinane, ayinavumba okanye ivumba kancinci, inyibilika ngokulula kwi-ethanol okanye i-acetone, inyibilika kwi-methanol, kwaye ayinyibiliki emanzini okanye kwi-chloroform.Isenzo se-pharmacological kukuthintela inkqubo ye-mitochondrial phosphorylation yeentshulube, ngaloo ndlela kuthintela ukuhlanganiswa kwe-adenosine triphosphate (ATP) kwiintshulube, okukhokelela ekubeni buthathaka ngokukhawuleza kwamandla e-metabolism yeentshulube kunye nokufa ekugqibeleni.I-Closantel sodium inokubulala ngokupheleleyo ukhwekhwe, iintwala zegazi, iintshulube, i-strongyloides, i-nematodes yezintso, i-whipworms, i-Burrow nematodes, i-supine mouth nematodes, i-radiation esophagus Flukes, i-capillary nematodes, iimpethu zesikhumba, iimpethu zempumlo zegusha, amakhalane, i-scabies, i-nematodes, i-Fasciola hepatica, iimpukane zesisu sehashe, i-lipoma canis kunye nezinye iintsholongwane zenkukhu zangaphakathi nangaphandle.Inefuthe elihle kwimibungu yeentlobo ngeentlobo ze-trematodes, i-nematodes kunye ne-arthropods;umsebenzi wayo wokugxotha umkhuhlane wenzelwe iFasciola hepatica, kwaye umsebenzi wayo wokugxotha imibungu ngokuchasene nenematodes kunye ne-arthropods ubukhulu becala lolohlobo lweesuckers.Umzimba wombungu wegazi okanye iplasma.Iimvavanyo zeklinikhi ezisebenzayo zibonise ukuba xa idosi ye-10 mg / kg ubunzima bomzimba, inefuthe elipheleleyo lokugxotha kwiigusha iFasciola hepatica, i-disc trematode yangaphambili kunye ne-posterior disc, i-lungworm kunye neninzi ye-nematodes ye-digestive tract ngaphakathi nangaphandle komzimba.Sesona siphumo sokubulala iintshulube kwiigusha.Eyona idosi.
Amalungiselelo
I-5%, i-10% i-injection ye-sodium ye-Closantel;
I-1% Ivermectin + 12.5% I-injection ye-sodium ye-Closantel;
I-5%, i-10% yokumiswa kwe-sodium ye-Closantel.
I-Hebei Veyong Pharmaceutical Co., Ltd, yasekwa kwi-2002, ehlala kwisiXeko saseShijiazhuang, kwiPhondo laseHebei, eChina, ecaleni kwe-Capital Beijing.Ulishishini elikhulu leyeza lezilwanyana eliqinisekisiweyo le-GMP, eline-R&D, imveliso kunye nokuthengiswa kwee-APIs zonyango lwezilwanyana, amalungiselelo, ukutya okuxutywe kwangaphambili kunye nezongezo zokutya.NjengeZiko lobuGcisa lePhondo, iVeyong iye yaseka inkqubo yeR&D ehlaziyiweyo yeyeza elitsha lezilwanyana, kwaye lishishini elaziwa kuzwelonke leteknoloji esekelwe kunyango lwezilwanyana, kukho iingcali zobugcisa ezingama-65.I-Veyong ineziseko ezimbini zokuvelisa: i-Shijiazhuang kunye ne-Ordos, apho isiseko se-Shijiazhuang sihlanganisa indawo ye-78,706 m2, kunye neemveliso ze-API ze-13 ezibandakanya i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kunye ne-11, i-injection oral solutions, i-injection oral solutions. , i-premix, i-bolus, i-pesticides kunye ne-disinfectant, njl.IVeyong ibonelela ngee-APIs, ngaphezulu kwe-100 yamalungiselelo eleyibhile, kunye nenkonzo ye-OEM & ODM.
I-Veyong ibona ukubaluleka okukhulu kulawulo lwenkqubo ye-EHS(Environment, Health & Safety), kwaye ifumene i-ISO14001 kunye nezatifikethi ze-OHSAS18001.I-Veyong idweliswe kumashishini amashishini asakhasayo anobuchule kwiPhondo laseHebei kwaye inokuqinisekisa ukubonelela ngokuqhubekayo kweemveliso.
I-Veyong yaseka inkqubo epheleleyo yolawulo lomgangatho, yafumana isatifikethi se-ISO9001, isatifikethi se-GMP sase-China, isiqinisekiso se-APVMA se-GMP sase-Australia, isatifikethi se-GMP sase-Ethiopia, isatifikethi se-Ivermectin CEP, kwaye siphumelele ukuhlolwa kwe-US FDA.I-Veyong ineqela lobuchwephesha lobhaliso, intengiso kunye nenkonzo yobugcisa, inkampani yethu ifumene ukuthembela kunye nenkxaso kubathengi abaninzi ngomgangatho wemveliso ogqwesileyo, umgangatho ophezulu wokuthengisa kwangaphambili kunye nenkonzo yasemva kokuthengisa, ulawulo olunzulu kunye nolwenzululwazi.I-Veyong yenze intsebenziswano yexesha elide kunye namashishini amaninzi amachiza ezilwanyana awaziwayo ngamazwe ngamazwe kunye neemveliso ezithunyelwa eYurophu, eMzantsi Melika, kuMbindi Mpuma, e-Afrika, e-Asia, njl. ngaphezu kwamazwe angama-60 kunye nemimandla.
