I-10% yesitofu se-Iron Dextran
Isenzo se-Pharmacological
I-Pharmacodynamics: I-iron iyona nto iphambili ye-hemoglobin kunye ne-myoglobin.IHemoglobin yeyona nto ithwala ioksijini kwiiseli ezibomvu zegazi.I-Myoglobin yindawo apho iiseli zezihlunu zigcina ioksijini ukunceda ukubonelela ngeoksijini ngexesha lokuzilolonga kwezihlunu.Uninzi lwee-enzymes kunye nezinto ezibandakanyekayo kumjikelezo we-tricarboxylic acid zinentsimbi, okanye zinokusebenza kuphela xa kukho intsimbi.Ke ngoko, emva kokufakwa kwentsimbi esebenzayo kwizilwanyana ezinqongopheleyo, ukongeza kwi-hemoglobin synthesis ekhawulezileyo, iimpawu ezinxulumene nokunqongophala kwe-iron kunye nokuncipha komsebenzi we-enzyme ene-iron njengokuncipha kokukhula, ukungahambi kakuhle kokuziphatha, kunye nokusilela ngokomzimba kunokulungiswa ngokuthe ngcembe.I-Pharmacokinetics Iron ye-injection, efakwe ngokukhawuleza kunomlomo;Ukugxininiswa kweplasma kuphezulu kwi-24 ~ 48 iiyure emva kwesitofu se-iron dextran, okt.
Iron dextraniimolekyuli zinkulu, zixutywe yimikhumbi ye-lymphatic kwaye emva koko zidluliselwe egazini, kwaye i-plasma concentration iyanda ngokukhawuleza;emva kwesitofu kwi-blood circulation okanye i-intramuscular injection, i-phagocytosed kwaye idibaniswe kwintsimbi kunye ne-dextran yinkqubo ye-monocyte-phagocyte.Emva kokufunxwa, ii-ion zentsimbi zixutywa yi-ceruloplasmin egazini ukuya kwii-ion ze-iron trivalent, ezithi ke zibophe kwi-receptorrin yokudlulisa kwaye zingene kwiiseli ngendlela ye-pinocytosis yeeseli ze-hematopoietic.Ziyakwazi ukuqokelela kwisibindi, i-spleen, i-bone marrow kunye nezinye iinkqubo ze-monocyte-phagocyte ngendlela ye-ferritin okanye i-hemosiderin.Iiprotheyini ezibophelelayo ziphezulu kwi-hemoglobin, iphantsi kwi-myoglobin, i-enzymes, kunye neeprotheni ezihambisa isinyithi, kunye ne-ferritin ephantsi okanye i-hemosiderin.
Isenzo kunye nokusetyenziswa
Amachiza okulwa ne-anemia.Ukusilela kwe-iron anemia kumathole, amathole, amantshontsho ehagu, amantshontsho kunye nezilwanyana ezinoboya.
Umthamo kunye noLawulo
Inaliti ye-Intramuscular: idosi enye, i-4 ~ 12ml yamathole kunye namathole;2 ~ 4ml zamantshontsho eehagu;I-0.4 ~ 4ml yeenjana;1 ~ 4ml yeempungutye;0.6 ~ 2ml ye-mink.
Iimpendulo Ezibi
Amantshontsho eehagu atofelwe ngentsimbi ngamanye amaxesha aye abe nokuma okungazinzanga ngenxa yobuthathaka bezihlunu, nto leyo enokubangela ukufa kwiimeko ezimandundu.
Ukulumkela
(1) Le mveliso inetyhefu enkulu kwaye ifuna ulawulo olungqongqo lwedosi yesitofu se-intramuscular.
(2)Inaliti ye-Intramuscular inokubangela intlungu yendawo kwaye kufuneka ifakwe ngokunzulu kwi-muscle.
(3)Ukutofa iihagu ezindala kuneeveki ezi-4 ubudala kunokubangela ukuba izihlunu zegluteal zibe nebala.
(4)Ifuna ukukhuselwa ekukhenkceni, kwaye imvula inokubakho emva kwexesha elide.
Iityuwa zentsimbi zinokusabela ngeekhemikhali ezininzi okanye iziyobisi, ngoko ke akufanele zilawulwe ngaxeshanye okanye zixutywe ngomlomo namanye amachiza.
Ixesha lokurhoxisa
Akufuni kuphuhliswa.
Ugcino
Khusela ekukhanyeni.
I-Hebei Veyong Pharmaceutical Co., Ltd, yasekwa kwi-2002, ehlala kwisiXeko saseShijiazhuang, kwiPhondo laseHebei, eChina, ecaleni kwe-Capital Beijing.Ulishishini elikhulu leyeza lezilwanyana eliqinisekisiweyo le-GMP, eline-R&D, imveliso kunye nokuthengiswa kwee-APIs zonyango lwezilwanyana, amalungiselelo, ukutya okuxutywe kwangaphambili kunye nezongezo zokutya.NjengeZiko lobuGcisa lePhondo, iVeyong iye yaseka inkqubo yeR&D ehlaziyiweyo yeyeza elitsha lezilwanyana, kwaye lishishini elaziwa kuzwelonke leteknoloji esekelwe kunyango lwezilwanyana, kukho iingcali zobugcisa ezingama-65.I-Veyong ineziseko ezimbini zokuvelisa: i-Shijiazhuang kunye ne-Ordos, apho isiseko se-Shijiazhuang sihlanganisa indawo ye-78,706 m2, kunye neemveliso ze-API ze-13 ezibandakanya i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kunye ne-11, i-injection oral solutions, i-injection oral solutions. , i-premix, i-bolus, i-pesticides kunye ne-disinfectant, njl.IVeyong ibonelela ngee-APIs, ngaphezulu kwe-100 yamalungiselelo eleyibhile, kunye nenkonzo ye-OEM & ODM.
I-Veyong ibona ukubaluleka okukhulu kulawulo lwenkqubo ye-EHS(Environment, Health & Safety), kwaye ifumene i-ISO14001 kunye nezatifikethi ze-OHSAS18001.I-Veyong idweliswe kumashishini amashishini asakhasayo anobuchule kwiPhondo laseHebei kwaye inokuqinisekisa ukubonelela ngokuqhubekayo kweemveliso.
I-Veyong yaseka inkqubo epheleleyo yolawulo lomgangatho, yafumana isatifikethi se-ISO9001, isatifikethi se-GMP sase-China, isiqinisekiso se-APVMA se-GMP sase-Australia, isatifikethi se-GMP sase-Ethiopia, isatifikethi se-Ivermectin CEP, kwaye siphumelele ukuhlolwa kwe-US FDA.I-Veyong ineqela lobuchwephesha lobhaliso, intengiso kunye nenkonzo yobugcisa, inkampani yethu ifumene ukuthembela kunye nenkxaso kubathengi abaninzi ngomgangatho wemveliso ogqwesileyo, umgangatho ophezulu wokuthengisa kwangaphambili kunye nenkonzo yasemva kokuthengisa, ulawulo olunzulu kunye nolwenzululwazi.I-Veyong yenze intsebenziswano yexesha elide kunye namashishini amaninzi amachiza ezilwanyana awaziwayo ngamazwe ngamazwe kunye neemveliso ezithunyelwa eYurophu, eMzantsi Melika, kuMbindi Mpuma, e-Afrika, e-Asia, njl. ngaphezu kwamazwe angama-60 kunye nemimandla.