I-Amoxicillin Umgubo onyibilikayo
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Ividiyo
Isenzo se-Pharmacological
Pharmacodynamics
I-Amoxicillin yi-β-lactam ye-antibiotic ene-antibacterial effect ebanzi.I-antibacterial spectrum kunye nomsebenzi we-antibacterial ngokusisiseko ziyafana nezo ze-ampicillin, kwaye umsebenzi we-antibacterial ngokuchasene neebhaktheriya ezininzi ze-Gram-positive buthathaka kancinci kunaleyo ye-penicillin.Inefuthe elinamandla kwiibhaktiriya ze-Gram-negative ezifana ne-Escherichia coli, i-Proteus, i-Salmonella, i-Haemophilus, i-Brucella kunye ne-Pasteurella, kodwa ezi bhaktiriya ziyakwazi ukumelana namachiza.Ayinabungozi kwiPseudomonas aeruginosa.Ngenxa yokuba ukufunxwa kwayo kwizilwanyana ze-monogastric kungcono kune-ampicillin kwaye ukuxinana kwayo kwegazi kuphezulu, kunesiphumo esingcono sonyango kusulelo lwenkqubo.Ilungele usulelo lwenkqubo olufana nenkqubo yokuphefumla, inkqubo yomchamo, ulusu kunye nezicubu ezithambileyo ezibangelwa ziibhaktheriya ezibuthathaka.
Pharmacokinetics
I-Amoxicillin izinzile kwi-asidi yesisu, kwaye i-74% ukuya kwi-92% ifunxa emva kokulawulwa komlomo kwizilwanyana ze-monogastric.Imixholo yendlela yesisu ichaphazela izinga lokufunxa, kodwa kungekhona iqondo lokufunxa, ngoko inokulawulwa ngokutya okuxutywe.Emva kokuthatha idosi efanayo ngomlomo, i-serum concentration ye-amoxicillin yi-1.5 ukuya kumaxesha ama-3 ngaphezulu kwe-ampicillin.
Ukusebenzisana kweziyobisi
(1) Ukudibanisa le mveliso kunye ne-aminoglycosides kunokunyusa ukuxinwa kokugqibela kwiibhaktheriya, kubonisa umphumo we-synergistic.(2) Ii-bacteriostatic agents ezikhawulezayo ezifana ne-macrolides, i-tetracyclines kunye ne-amide alcohols ziphazamisa umphumo we-bactericidal wale mveliso, kwaye akufanele zisetyenziswe kunye.
Isenzo kunye nokusetyenziswa
β-lactam antibiotics.Kunyango lwe-amoxicillin-susceptible gram-positive kunye ne-gram-negative usulelo kwiinkukhu.
Umthamo kunye nokusetyenziswa
Ngokusekelwe kule mveliso.Ukulawulwa komlomo: idosi enye, nge-1kg ubunzima bomzimba, inkukhu 0.2-0.3g, kabini ngosuku, iintsuku ezi-5;isiselo esixutywe: nge-1L yamanzi, inkukhu 0.6g, iintsuku ezi-3-5.
Ukusabela kakubi
Unempembelelo enamandla yokuphazamiseka kwi-flora eqhelekileyo yendlela yesisu.
Ukulumkela
(1) Akuvumelekanga ukuba iinkukhu ezizalela ngexesha lokubeka.
(2) Usulelo lwentsholongwane yegram-positive ekwaziyo ukumelana nepenicillin akufanele kusetyenziswe.
(3) Ulwabiwo lwangoku kunye nokusetyenziswa.
Ixesha lokurhoxisa
Iintsuku ezisi-7 kwiinkukhu.
Ugcino
shading, ukugcinwa okutywiniweyo
I-Hebei Veyong Pharmaceutical Co., Ltd, yasekwa kwi-2002, ehlala kwisiXeko saseShijiazhuang, kwiPhondo laseHebei, eChina, ecaleni kwe-Capital Beijing.Ulishishini elikhulu leyeza lezilwanyana eliqinisekisiweyo le-GMP, eline-R&D, imveliso kunye nokuthengiswa kwee-APIs zonyango lwezilwanyana, amalungiselelo, ukutya okuxutywe kwangaphambili kunye nezongezo zokutya.NjengeZiko lobuGcisa lePhondo, iVeyong iye yaseka inkqubo yeR&D ehlaziyiweyo yeyeza elitsha lezilwanyana, kwaye lishishini elaziwa kuzwelonke leteknoloji esekelwe kunyango lwezilwanyana, kukho iingcali zobugcisa ezingama-65.I-Veyong ineziseko ezimbini zokuvelisa: i-Shijiazhuang kunye ne-Ordos, apho isiseko se-Shijiazhuang sihlanganisa indawo ye-78,706 m2, kunye neemveliso ze-API ze-13 ezibandakanya i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kunye ne-11, i-injection oral solutions, i-injection oral solutions. , i-premix, i-bolus, i-pesticides kunye ne-disinfectant, njl.IVeyong ibonelela ngee-APIs, ngaphezulu kwe-100 yamalungiselelo eleyibhile, kunye nenkonzo ye-OEM & ODM.
I-Veyong ibona ukubaluleka okukhulu kulawulo lwenkqubo ye-EHS(Environment, Health & Safety), kwaye ifumene i-ISO14001 kunye nezatifikethi ze-OHSAS18001.I-Veyong idweliswe kumashishini amashishini asakhasayo anobuchule kwiPhondo laseHebei kwaye inokuqinisekisa ukubonelela ngokuqhubekayo kweemveliso.
I-Veyong yaseka inkqubo epheleleyo yolawulo lomgangatho, yafumana isatifikethi se-ISO9001, isatifikethi se-GMP sase-China, isiqinisekiso se-APVMA se-GMP sase-Australia, isatifikethi se-GMP sase-Ethiopia, isatifikethi se-Ivermectin CEP, kwaye siphumelele ukuhlolwa kwe-US FDA.I-Veyong ineqela lobuchwephesha lobhaliso, intengiso kunye nenkonzo yobugcisa, inkampani yethu ifumene ukuthembela kunye nenkxaso kubathengi abaninzi ngomgangatho wemveliso ogqwesileyo, umgangatho ophezulu wokuthengisa kwangaphambili kunye nenkonzo yasemva kokuthengisa, ulawulo olunzulu kunye nolwenzululwazi.I-Veyong yenze intsebenziswano yexesha elide kunye namashishini amaninzi amachiza ezilwanyana awaziwayo ngamazwe ngamazwe kunye neemveliso ezithunyelwa eYurophu, eMzantsi Melika, kuMbindi Mpuma, e-Afrika, e-Asia, njl. ngaphezu kwamazwe angama-60 kunye nemimandla.
