20% Florfenicol WSP
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Ividiyo
Pharmacodynamics
I-Flofenicol yi-wide-spectrum amide alcohol antibiotic kunye ne-bacteriostatic agent, esebenza ngokuthintela ukuhlanganiswa kweeprotheni zebhaktheriya ngokuzibophelela kwi-subunit ye-50S ye-ribosome.Inomsebenzi onamandla we-antibacterial ngokuchasene neentlobo zebhaktheriya zegram-positive kunye negram-negative.I-Pasteurella hemolytica, i-Pasteurella multocida, kunye ne-Actinobacillus pleuropneumoniae zisengozini kakhulu kwi-florfenicol.Umsebenzi we-antibacterial we-florfenicol ngokuchasene ne-microorganisms ezininzi kwi-vitro ufana okanye unamandla kunaleyo ye-thiamphenicol, kwaye ezinye iibhaktheriya ezikwazi ukumelana ne-amide alcohols ngenxa ye-acetylation, njenge-Escherichia coli kunye ne-Klebsiella pneumoniae, zisenoBuntu kwi-florfenicol.
Isetyenziswa ikakhulu kwizifo zebhaktiriya zeehagu, iinkukhu kunye neentlanzi ezibangelwa ziintsholongwane ezibuthathaka, ezifana nezifo zokuphefumla zenkomo neehagu ezibangelwa yi Pasteurella hemolytica, Pasteurella multocida kunye ne Actinobacillus pleuropneumoniae.I-typhoid fever kunye ne-paratyphoid fever ebangelwa yi-Salmonella, ikholera yenkukhu, i-pullorum, i-Escherichia coli, njl.;iibhaktheriya zeentlanzi ezibangelwa yiPasteurella, Vibrio, Staphylococcus aureus, Hydromonas, Enteritidis, njl. I-Sepsis, i-enteritis, isifo sesikhumba esibomvu, njl.
Pharmacokinetics
Ulawulo lomlomo lwe-florfenicol lufunxwa ngokukhawuleza, kwaye ugxininiso lonyango lunokufikelelwa egazini emva kweyure eli-1, kwaye i-concentration ye-peak yegazi inokufikelela kwiiyure ezi-1 ukuya kwezi-3.I-bioavailability ingaphezulu kwe-80%.I-Flofenicol isasazwa ngokubanzi kwizilwanyana kwaye inokudlula kumqobo wegazi-ubuchopho.Ikakhulu ikhutshwe kwifom ye-original evela kumchamo, kwaye ixabiso elincinci likhutshwe kunye neefeces.
Ukusebenzisana kweziyobisi
(1) I-Macrolides kunye ne-lincosamides zineenjongo ezifanayo zesenzo njengale mveliso, zombini ziboshwe kwi-subunit ye-50S ye-ribosome yebhakteria, kwaye inokuvelisa ukuchasana okufanayo xa isetyenziswe ngokudibeneyo.(2) Isenokuchasa umsebenzi we-bactericidal we-penicillin okanye i-aminoglycosides, kodwa ayizange iboniswe kwizilwanyana.
Isenzo kunye nokusetyenziswa
Amide antibiotics utywala.Kuba usulelo lwe-Pasteurella kunye ne-Escherichia coli.
Ukusetyenziswa kunye nomthamo
Ngokusekelwe kule mveliso.Ukulawulwa komlomo: nge-1kg ubunzima bomzimba, 0.1 ~ 0.15g yeehagu kunye neenkukhu.Amaxesha ama-2 ngosuku ngeentsuku ezi-3 ukuya kwezi-5.Intlanzi 50 ~ 75mg.Ixesha eli-1 ngosuku ngeentsuku ezi-3 ukuya kwezi-5.
Ukusabela kakubi
I-20% ye-Florfenicol i-powder e-soluble yamanzi inomphumo othile we-immunosuppressive xa isetyenziswe kwi-dose ephezulu kune-dose ephakanyisiweyo.
Ingqalelo
(1) Iinkukhu ezibeka amaqanda ukuze zityiwe ngabantu akufanele zisetyenziswe ngexesha lokubeka amaqanda;(2) Sebenzisa ngononophelo kubafuyi.Ine-embryotoxicity kwaye kufuneka isetyenziswe ngononophelo kwimfuyo ekhulelweyo kunye neyanyisayo;(3) I-contraindicated ngexesha lokugonywa okanye kwizilwanyana ezine-immunodeficiency enzima;(4) Kwizilwanyana ezinokusilela kwezintso, umthamo kufuneka uncitshiswe ngokufanelekileyo okanye ixesha lokudosa kufuneka landiswe.
Ixesha lokurhoxisa
Iihagu iintsuku ezingama-20, iinkukhu ezi-5;Iintsuku ze-375 degree zentlanzi.
Ugcino
Gcina uvaliwe kwaye kwindawo eyomileyo
I-Hebei Veyong Pharmaceutical Co., Ltd, yasekwa kwi-2002, ehlala kwisiXeko saseShijiazhuang, kwiPhondo laseHebei, eChina, ecaleni kwe-Capital Beijing.Ulishishini elikhulu leyeza lezilwanyana eliqinisekisiweyo le-GMP, eline-R&D, imveliso kunye nokuthengiswa kwee-APIs zonyango lwezilwanyana, amalungiselelo, ukutya okuxutywe kwangaphambili kunye nezongezo zokutya.NjengeZiko lobuGcisa lePhondo, iVeyong iye yaseka inkqubo yeR&D ehlaziyiweyo yeyeza elitsha lezilwanyana, kwaye lishishini elaziwa kuzwelonke leteknoloji esekelwe kunyango lwezilwanyana, kukho iingcali zobugcisa ezingama-65.I-Veyong ineziseko ezimbini zokuvelisa: i-Shijiazhuang kunye ne-Ordos, apho isiseko se-Shijiazhuang sihlanganisa indawo ye-78,706 m2, kunye neemveliso ze-API ze-13 ezibandakanya i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kunye ne-11, i-injection oral solutions, i-injection oral solutions. , i-premix, i-bolus, i-pesticides kunye ne-disinfectant, njl.IVeyong ibonelela ngee-APIs, ngaphezulu kwe-100 yamalungiselelo eleyibhile, kunye nenkonzo ye-OEM & ODM.
I-Veyong ibona ukubaluleka okukhulu kulawulo lwenkqubo ye-EHS(Environment, Health & Safety), kwaye ifumene i-ISO14001 kunye nezatifikethi ze-OHSAS18001.I-Veyong idweliswe kumashishini amashishini asakhasayo anobuchule kwiPhondo laseHebei kwaye inokuqinisekisa ukubonelela ngokuqhubekayo kweemveliso.
I-Veyong yaseka inkqubo epheleleyo yolawulo lomgangatho, yafumana isatifikethi se-ISO9001, isatifikethi se-GMP sase-China, isiqinisekiso se-APVMA se-GMP sase-Australia, isatifikethi se-GMP sase-Ethiopia, isatifikethi se-Ivermectin CEP, kwaye siphumelele ukuhlolwa kwe-US FDA.I-Veyong ineqela lobuchwephesha lobhaliso, intengiso kunye nenkonzo yobugcisa, inkampani yethu ifumene ukuthembela kunye nenkxaso kubathengi abaninzi ngomgangatho wemveliso ogqwesileyo, umgangatho ophezulu wokuthengisa kwangaphambili kunye nenkonzo yasemva kokuthengisa, ulawulo olunzulu kunye nolwenzululwazi.I-Veyong yenze intsebenziswano yexesha elide kunye namashishini amaninzi amachiza ezilwanyana awaziwayo ngamazwe ngamazwe kunye neemveliso ezithunyelwa eYurophu, eMzantsi Melika, kuMbindi Mpuma, e-Afrika, e-Asia, njl. ngaphezu kwamazwe angama-60 kunye nemimandla.
