I-0.5% ye-Eprinomectin Galela kwiSisombululo
Isenzo se-Pharmacological
Eprinomectinyeye-macrolide insecticides, enefuthe elisebenzayo le-anthelmintic kwi-parasite yangaphakathi nangaphandle, ngakumbi i-nematodes kunye ne-arthropods, ngokunyusa ukukhululwa kwe-γ-aminobutyric acid (γ-GABA), i-transmitter inhibitory ye-parasite, kunye nokuvula i-glutamate. -i-chloride channels ezilawulwayo, ukuphucula ukunyanzeliswa kwe-nerve membrane kwi-ion ye-chloride ukuze kuthintelwe ukuhanjiswa kweempawu ze-nerve, ekugqibeleni kukhokelela ekukhubazekeni kwe-nerve ye-parasite kunye nokulahlekelwa kwekhono le-contractile yeeseli ze-muscle kunye nokufa.
Isenzo se-Pharmacological
Eprinomectini-soluble, kwaye i-pharmacokinetics yayo ibonisa iimpawu ezingabonakaliyo.Xa i-0.5 mg / kg · i-bw igalelwe ngasemva kweenkomo zobisi, i-peak concentration (Cmax) yayiyi-18.64 ± 2.51 ng / ml, kwaye ixesha lokugxila kwi-peak (Tmax) yayiyi-3.63 ± 0.92 iintsuku, ithetha ixesha lokuhlala (MRT). ) 5.61 ± 0.45 iintsuku, indawo ephantsi kwegophe (AUC0-t) 113.90 ± 19.01 ng · imini ml, umthamo obonakalayo wokusabalalisa (Vd) 41 L, ukukhutshwa kweplasma (CL) 4.5 L / ngosuku, ngokukodwa kukhutshwe kwindle, kunye ne isixa esincinci esikhutshwa ngobisi kunye nomchamo.
Isalathiso
I-Eprinomectin Pour kwisisombululo isetyenziselwa ukunyanga izifo ze-parasitic ezifana ne-nematodes kunye ne-mites in vitro kwiinkomo zobisi.
Umthamo kunye noLawulo
Ibalwe njenge-Eprinomectin.Ukusetyenziswa kwangaphandle, ngokuthe ngcembe ugalele i-0.5 mg yeenkomo nge-1 kg yobunzima bomzimba ecaleni komqolo weenkomo zobisi ukusuka kwisikhonkwane ukuya kumazantsi omsila (okt, i-1 ml yale mveliso nge-10 kg yobunzima bomzimba).
Ukulumkela
1. ukusetyenziswa kwangaphandle kwimfuyo kuphela.Musa ukusebenzisa kwiindawo zolusu ezinokhwekhwe, izilonda zolusu, udaka, kunye nelindle.
2. Ukuba imveliso ifakwe emkhenkceni, kufuneka inyibilike ngokupheleleyo kwaye ishukunyiswe kakuhle ngaphambi kokusetyenziswa.
3. Kuphephe ukuba sesichengeni sabantwana kwiziyobisi.
4. Iibhotile zeziyobisi ezisetyenzisiweyo kunye nolwelo lweziyobisi olushiyekileyo luyakulahlwa ngokukhuselekileyo (njengokungcwatywa).
Ukusabela kakubi
Xa isetyenziswe kwi-dose echaziweyo, akukho zithintelo ezibi zabonwa.
Ixesha lokurhoxisa
iintsuku ezi-0.
Iphakheji
200ml/ibhotile, 1L/ibhotile, 2L/ibhotile, 5L/ibhotile
Ugcino
Gcina kwindawo evaliweyo engaphantsi kwe-30 ℃, ekhuselwe ekukhanyeni.
I-Hebei Veyong Pharmaceutical Co., Ltd, yasekwa kwi-2002, ehlala kwisiXeko saseShijiazhuang, kwiPhondo laseHebei, eChina, ecaleni kwe-Capital Beijing.Ulishishini elikhulu leyeza lezilwanyana eliqinisekisiweyo le-GMP, eline-R&D, imveliso kunye nokuthengiswa kwee-APIs zonyango lwezilwanyana, amalungiselelo, ukutya okuxutywe kwangaphambili kunye nezongezo zokutya.NjengeZiko lobuGcisa lePhondo, iVeyong iye yaseka inkqubo yeR&D ehlaziyiweyo yeyeza elitsha lezilwanyana, kwaye lishishini elaziwa kuzwelonke leteknoloji esekelwe kunyango lwezilwanyana, kukho iingcali zobugcisa ezingama-65.I-Veyong ineziseko ezimbini zokuvelisa: i-Shijiazhuang kunye ne-Ordos, apho isiseko se-Shijiazhuang sihlanganisa indawo ye-78,706 m2, kunye neemveliso ze-API ze-13 ezibandakanya i-Ivermectin, i-Eprinomectin, i-Tiamulin Fumarate, i-Oxytetracycline hydrochloride ects, kunye ne-11, i-injection oral solutions, i-injection oral solutions. , i-premix, i-bolus, i-pesticides kunye ne-disinfectant, njl.IVeyong ibonelela ngee-APIs, ngaphezulu kwe-100 yamalungiselelo eleyibhile, kunye nenkonzo ye-OEM & ODM.
I-Veyong ibona ukubaluleka okukhulu kulawulo lwenkqubo ye-EHS(Environment, Health & Safety), kwaye ifumene i-ISO14001 kunye nezatifikethi ze-OHSAS18001.I-Veyong idweliswe kumashishini amashishini asakhasayo anobuchule kwiPhondo laseHebei kwaye inokuqinisekisa ukubonelela ngokuqhubekayo kweemveliso.
I-Veyong yaseka inkqubo epheleleyo yolawulo lomgangatho, yafumana isatifikethi se-ISO9001, isatifikethi se-GMP sase-China, isiqinisekiso se-APVMA se-GMP sase-Australia, isatifikethi se-GMP sase-Ethiopia, isatifikethi se-Ivermectin CEP, kwaye siphumelele ukuhlolwa kwe-US FDA.I-Veyong ineqela lobuchwephesha lobhaliso, intengiso kunye nenkonzo yobugcisa, inkampani yethu ifumene ukuthembela kunye nenkxaso kubathengi abaninzi ngomgangatho wemveliso ogqwesileyo, umgangatho ophezulu wokuthengisa kwangaphambili kunye nenkonzo yasemva kokuthengisa, ulawulo olunzulu kunye nolwenzululwazi.I-Veyong yenze intsebenziswano yexesha elide kunye namashishini amaninzi amachiza ezilwanyana awaziwayo ngamazwe ngamazwe kunye neemveliso ezithunyelwa eYurophu, eMzantsi Melika, kuMbindi Mpuma, e-Afrika, e-Asia, njl. ngaphezu kwamazwe angama-60 kunye nemimandla.